Alterations in homologous recombination repair genes in prostate

Targeting homologous recombination deficiency (HRD) in cancer research - SOPHiA GENETICS

Homologous Recombination Deficiency

Role of the DNA damage response in prostate cancer formation, progression and treatment

ESMO 2019: Central, Prospective Detection of Homologous Recombination Repair Gene Mutations in Tumor Tissue from >4000 Men with mCRPC Screened for the PROfound Study

Homologous recombination repair pathway (adapted from De Picciotto et

High prevalence of DNA damage repair gene defects and TP53 alterations in men with treatment-naïve metastatic prostate cancer –Results from a prospective pilot study using a 37 gene panel - ScienceDirect

Discovering a qualitative transcriptional signature of homologous recombination defectiveness for prostate cancer - ScienceDirect

Cancers, Free Full-Text

Genetic testing for homologous recombination repair (HRR) in metastatic castration-resistant prostate cancer (mCRPC): challenges and solutions

Preclinical In Vivo Validation of the RAD51 Test for Identification of Homologous Recombination-Deficient Tumors and Patient Stratification - Xentech

Homologous recombination

Pan-cancer landscape of homologous recombination deficiency

Targeting the DNA Repair Enzyme Polymerase θ in Cancer Therapy: Trends in Cancer

RB1 loss overrides PARP inhibitor sensitivity driven by RNASEH2B loss in prostate cancer