Advanced Quantitative Fluorescence Microscopy to Probe the Molecular Dynamics of Viral Entry, Science Lab

Viral entry into the host cell requires the coordination of many cellular and viral proteins in a precise order. Modern microscopy techniques are now allowing researchers to investigate these interactions with higher spatiotemporal resolution than ever before. Here we present two examples from the field of HIV research that make use of an innovative quantitative imaging approach as well as cutting edge fluorescence lifetime-based confocal microscopy methods to gain novel insights into how HIV fuses to cell membranes and enters the cell.

A chimeric virus-based probe unambiguously detects live circulating tumor cells with high specificity and sensitivity - ScienceDirect

Processes, Free Full-Text

2021 Top 10 Innovations The Scientist Magazine®

Mucins Inhibit Coronavirus Infection in a Glycan-Dependent Manner

Advancements in detection of SARS-CoV-2 infection for confronting COVID-19 pandemics - Laboratory Investigation

Single molecule imaging simulations with advanced fluorophore photophysics

Molecular beacons. (a) The most common molecular beacon structure is a

Natural Product Chemistry

Microscopy in Virology, Science Lab

Lighting up the Native Viral RNA Genome with a Fluorogenic Probe for the Live-Cell Visualization of Virus Infection

Amelioration of SARS-CoV-2 infection by ANO6 phospholipid scramblase inhibition - ScienceDirect

IJMS, Free Full-Text

Debulking SARS-CoV-2 in saliva using angiotensin converting enzyme 2 in chewing gum to decrease oral virus transmission and infection: Molecular Therapy